Mrs. Knight, aged 65, has been a patient of yours for many years. She has had a history of many complaints, and was diagnosed as hypertensive 5 years ago. She has had courses of various drugs for most of this time but has been unable to continue because of side effects. Your records reveal the following responses that were regarded as side effects.

• Diuretics - lethargy.
• Beta-blockers - nightmares.
• Dihydropyridine calcium channel blocker - headaches.
• Ace inhibitor - cough.

She returns to tell you that her cough disappeared a few days after stopping her ACE Inhibitor. She says she is well but is worried about her BP, but she is not keen about trying any other drugs. She has been off medication for two weeks now. Her BP is 150/100.